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February 16, 2007

Use of a Novel Topical Hemostatic Sealant in Lacrimal Surgery: A Prospective, Comparative Study

Ophthalmic Plastic & Reconstructive Surgery. January/February 2007.

FloSeal Matrix is a new, two-component (collagen granules and thrombin), topical hemostatic sealant. FloSeal was used during surgery in 10 consecutive patients undergoing DCR. A further 10 consecutive patients (comparative group) had DCR without FloSeal; nasal packing was performed to control postoperative bleeding. The severity of postoperative bleeding and patient comfort were compared between the two groups at three time points (immediately after surgery, 12 hours after surgery, and 24 hours after surgery).
All patients in the comparative group had some degree of postoperative bleeding (minimal to severe), whereas the nine patients in the FloSeal group had none or minimal bleeding. The difference was statistically significant at all three measured time points (p = 0.047, 0.006, 0.05). The FloSeal group also had less postoperative discomfort (p = 0.0001).
Conclusions: FloSeal Matrix is an effective hemostasis adjunct in patients undergoing lacrimal surgery. It has the added benefits of high patient satisfaction and ease of use.

Posted by afarahi at February 16, 2007 06:02 PM

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