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May 26, 2006
Continued monitoring indicated for AMD patients who have occult with no classic subfoveal CNV lesions
Archives of Ophthalmology, May 2006
In this fourth report from the Verteporfin in Photodynamic Therapy (VIP) Trial, follow-up angiograms in which classic CNV was identified were re-analyzed to determine how many occult with no classic lesions converted to predominantly classic or minimally classic composition at a follow-up examination. By 24 months, 8 percent of 89 patients had lesions that converted to predominantly classic composition, and 46 percent had minimally classic composition. The authors recommend monitoring, rather than ending follow-up, for these patients. If visual acuity decreases or predominantly classic features develop, photodynamic therapy with verteporfin or pegaptanib sodium injections may be considered, as long as the lesion has not become too large or visual acuity too poor before conversion or deterioration that verteporfin therapy or pegaptanib injections would no longer be meaningful to the patient.
Posted by kjalali at May 26, 2006 10:33 PM