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May 28, 2005
Automated Lamellar Keratoplasty for Recurrent Granular Corneal Dystrophy After Phototherapeutic Keratectomy
JOURNAL OF REFRACTIVE SURGERY Vol. 21 No. 3 May/June 2005
We performed a prospective interventional noncomparative case study of nine eyes (seven patients) with severe recurrent granular corneal dystrophy after PTK. An automated microkeratome was used to cut partial-thickness sections through the anterior surface of the donor and host corneas. The donor disc was placed on the recipient bed with four or eight interrupted sutures. The sutures were removed between 4 and 6 weeks postoperatively. During a mean follow-up period of 18.9±4.1 months, all grafts were transparent without visible opacity at the interface, and no serious complications occurred. In all cases, the visual acuity improved: seven eyes had best spectacle-corrected visual acuity of ≥20/40; two eyes reached 20/25. At last follow-up >12 months postoperatively, the mean corneal refractive power had significantly increased by 2.34±0.93 diopters (D) (P<.001), and the corneal astigmatism significantly decreased by 0.91±0.98 D (P<.05). The mean corneal thickness was 477.4±26.9 µm preoperatively and 507.8±23.4 µm at last follow-up (P<.001). CONCLUSIONSOur findings suggest that automated lamellar keratoplasty for the treatment of recurrent granular corneal dystrophy is a safe and effective method of improving visual acuity, but recurrence remains a risk. [J Refract Surg. 2005;21:288-293.]
Posted by mehdi khanlari at May 28, 2005 11:41 PM