April 25, 2003
Transconjunctival mitomycin-C in needle revisions of failing filtering blebs
ophthalmology/ 2003/ April
PURPOSE: To report the efficacy and safety of transconjunctival mitomycin-C as an adjunct to needle revision of failing filtering blebs. METHODS: Needling of the bleb was performed with a 25-gauge needle. The site of the needle puncture was sutured and followed by application of transconjunctival mitomycin-C (0.5 mg/ml) by means of a sponge left in contact with the conjunctival epithelium for 6 minutes. RESULTS: Mean preoperative intraocular pressure was 22.1 ± 8.0 mmHg, which was reduced by 9.6 ± 7.9 mmHg to a mean postoperative intraocular pressure of 12.5 ± 6.1 mmHg. Kaplan-Meier survival analysis showed a probability of continued success at 12 months of 76.1%, and at 24 months of 71.6%. The most common complication was hyphema in 7.1% of patients. Twenty-six eyes also received postoperative injections of 5-fluorouracil. CONCLUSIONS: Transconjunctival mitomycin-C may enhance success of the needling procedure in failing filtering blebs.
Posted by pakravanmd at April 25, 2003 08:19 PM